I am currently working in top most MNC company if i have to go then have to leave my job will i be able to do job over there? or should I go with further studies(MS) which will be best option for me? please suggest?
The best option is to study on F1 visa and find a job.
There is no way that a employer can hire you now, as the H1 season just got done last week (unless you had a previous H1 approved already) and teh next season opens in April 2018. You can very well try for jobs in NGO’s and non-profit organizations who may apply for H1 all through the year outside of the quota.